Computational Ocularscience Laboratory

Our laboratory studies the structural and functional aspects of the eye under normal health and disease conditions with computational science and engineering.  Currently, we are focussed on understanding the mechanism of vision loss in glaucoma and developing biomarkers of glaucoma progression from experimental glaucoma studies and translational clinical studies.

Our strong interdisciplinary research efforts are structured to make significant contributions to the relevant areas in computing, mathematics, statistics and engineering.  And the central goals of our research efforts are biological and anatomical in nature to further our understanding of the anatomy, function and pathogenesis of ocular diseases, to benefit human health, to improve quality of life, and to minimize healthcare costs related to vision health.

Our laboratory is equipped to conduct basic, experimental and clinical glaucoma studies; equipped for modeling biosolid, biofluid and their interaction mechanics in the eye; and equipped for conducting functional electrophysiological ex vivo studies of the eye.  We also have essential engineering and computing resources to develop technology necessary for our research studies.  Our research projects are currently supported by research funding from the National Eye Institute (NEI) and the National Institutes of Health (NIH).

The computational ocularscience laboratory was founded and directed by Madhusudhanan Balasubramanian, Ph.D.  Dr. Balasubramanian has strong multidisciplinary interests, training and experience to study ocular structure and function integrated within the framework of computational science and engineering.  He is a recipient of the K99/R00 Pathway to Independence award from the National Eye Institute / National Institutes of Health in 2011; recipient of the Imaging and Perimetry Society-Heidelberg Engineering Young Researcher award on “Relationship of Morphology and Function” in 2010; and the 1998 PSG College of Technology Alumni Award for the best Bachelor of Engineering project in Electrical and Electronics Engineering.