Publications


  • Untitled Document PEER-REVIEWED JOURNAL PUBLICATIONS
    1. Belghith A, Bowd C, Medeiros FA, Balasubramanian M, Weinreb RN, Zangwill LM, ``Learning from healthy and stable eyes: a new approach for detection of glaucomatous progression'', Journal of Medical Imaging, In Press. 
    2. Belghith A, Bowd C, Medeiros FA, Balasubramanian M, Weinreb RN, Zangwill LM, ``Glaucoma progression detection using nonlocal Markov random field prior'', Journal of Medical Imaging, Vol. 1, No. 3, 2014, article id: 034504.
    3. Balasubramanian M, Arias-Castro E, Medeiros FA, Kriegman DJ, Bowd C, Weinreb RN, Holst M, Sample PA, Zangwill LM, "Detecting Glaucoma Progression From Localized Rates of Retinal Changes in Parametric and Nonparametric Statistical Framework With Type I Error Control", Investigative ophthalmology & visual science, Vol. 55, No. 3, 2014, pp. 1684-1695; PMID: 24519427.
    4. Bowd C, Weinreb RN, Balasubramanian M, Lee I, Jang G, Yousefi S, Zangwill LM, Medeiros FA, Girkin CA, Liebmann JM, Goldbaum MH, "Glaucomatous Patterns in Frequency Doubling Technology (FDT) Perimetry Data Identified by Unsupervised Machine Learning Classifiers", PLOS ONE, Vol. 9, No. 1, 2014, e85941; PMID: 24497932.
    5. Belghith A, Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM, "A unified framework for glaucoma progression detection using Heidelberg Retina Tomograph images", Computerized Medical Imaging and Graphics, Vol. 38, No. 5, 2014; pp. 411-4120; PMID: 24709053.
    6. Yousefi S, Goldbaum MH, Balasubramanian M, Medeiros FA, Zangwill LM, Liebmann JM, Girkin CA, Weinreb RN, Bowd C, "Learning from data: Recognizing glaucomatous defect patterns and detecting progression from visual field measurements", IEEE Transactions on Biomedical Engineering, Vol. 61, No. 7, 2014, pp. 2112-2124; PMID: 24710816.
    7. Yousefi S, Goldbaum MH, Balasubramanian M, Jung T, Weinreb RN, Medeiros FA, Zangwill LM, Liebmann JM, Girkin CA, Bowd C, "Glaucoma Progression Detection using Structural Retinal Nerve Fiber Layer Measurements and Functional Visual Field Points", IEEE Transactions on Biomedical Engineering, Vol. 61, No. 4, pp. 1143-1154; PMID: 24658239.
    8. Belghith A, Bowd C, Balasubramanian M, Weinreb RN, Zangwill LM, "A Bayesian framework for glaucoma progression detection using Heidelberg Retina Tomograph images", International Journal of Advanced Computer Science and Applications, Vol. 4, No.9, 2013, pp. 222-228.
    9. Goldbaum MH, Lee I, Jang G, Balasubramanian M, Sample PA, Weinreb RN, Liebmann JM, Girkin CA, Anderson DR, Zangwill LM, Fredette MJ, Jung TP, Medeiros F, Bowd C, "Progression of Patterns (POP): A Machine Classifier Algorithm to Identify Glaucoma Progression in Visual Fields", Investigative Ophthalmology and Visual Science, Investigative Ophthalmology and Visual Science, Vol. 53, No. 10, 2012, pp.6557-6567; PMID: 22786913.
    10. Balasubramanian M, Kriegman DJ, Bowd C, Holst M, Weinreb RN, Sample PA, Zangwill LM, "Localized Glaucomatous Change Detection within the Proper Orthogonal Decomposition Framework", Investigative Ophthalmology and Visual Science, Vol. 53, No. 7, 2012, pp.3615-3628; PMID: 22491406.
    11. Bowd C, Lee I, Goldbaum MH, Balasubramanian M, Medeiros FA, Zangwill LM, Girkin CA, Liebmann JM, Weinreb RN, "Predicting Glaucomatous Progression in Glaucoma Suspect Eyes using Relevance Vector Machine Classifiers for Combined Structural and Functional Measurements", Investigative Ophthalmology and Visual Science, Vol. 53, No. 4, 2012, pp.2382-2389; PMID: 22427577.
    12. Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM, "Agreement between the Heidelberg Retina Tomograph (HRT) Stereometric Parameters Estimated Using HRT-I and HRT-II", Feature Issue on Glaucoma: Recent Discoveries and Patient Care, Optometry and Vision Science, Vol. 88, No. 1, 2011, pp.140-149; PMID: 21037499.
    13. Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM, "Agreement between Heidelberg Retina Tomograph (HRT-I) and HRT-II in Detecting Glaucomatous Changes Using Topographic Change Analysis (TCA)", Eye, Vol. 25, No. 1, 2011, pp.31-42; PMID: 20885428.
    14. Vizzeri G, Bowd C, Weinreb RN, Balasubramanian M, Medeiros FA, Sample PA, Zangwill LM. "Determinants of agreement between the Confocal Scanning Laser Tomograph and standardized assessment of glaucomatous progression", Ophthalmology, Vol. 117, No. 10, 2010, pp.1953-1959; PMID: 20557941.
    15. Balasubramanian M, Bowd C, Weinreb RN, Vizzeri G, Alencar LM, Sample PA, O'Leary N, Zangwill LM. "Clinical Evaluation of the Proper Orthogonal Decomposition Framework for Detecting Glaucomatous Changes in Human Subjects", Investigative Ophthalmology and Visual Science, Vol. 51, No. 1, 2010, pp.264-271; PMID: 19661228.
    16. Balasubramanian M, Zabic S, Bowd C, Thompson HW, Wolenski P, Iyengar SS, Karki BB, Zangwill LM. "A Framework for Detecting Glaucomatous Progression in the Optic Nerve Head of an Eye using Proper Orthogonal Decomposition", IEEE Transactions on Information Technology in Biomedicine, Vol. 13, No. 5, 2009, pp.781-793; PMID: 19369163.
    17. Vizzeri G, Balasubramanian M, Bowd C, Weinreb RN, Medeiros FA, Zangwill LM. "Spectral Domain-Optical Coherence Tomography to Detect Localized Retinal Nerve Fiber Layer Defects in Glaucomatous Eyes", Optics Express, Vol. 17, No. 5, 2009, pp. 4004-4018; PMID: 19259242.
    18. Balasubramanian M, Bowd C, Vizzeri G, Weinreb RN, Zangwill LM. "Effect of Image Quality on Tissue Thickness Measurements Obtained with Spectral Domain-Optical Coherence Tomography", Optics Express, Vol.17, No.5, 2009, pp. 4019-36; PMID: 19259243.
    19. Bowd C, Balasubramanian M, Weinreb RN, Vizzeri G, Alencar LM, O'Leary N, Sample PA, Zangwill LM. "Performance of Confocal Scanning Laser Tomograph Topographic Change Analysis (TCA) for Assessing Glaucomatous Progression", Investigative Ophthalmology and Visual Science, Vol. 50, No. 2, February 2009, pp. 691-701; PMID: 18836168.
    20. Vizzeri G, Weinreb RN, Martinez de la Casa JM, Alencar LM, Bowd C, Balasubramanian M, Medeiros FA, Sample P, Zangwill LM. "Clinicians Agreement in Establishing Glaucomatous Progression Using the Heidelberg Retina Tomograph", Ophthalmology, Vol. 116, No. 1, January 2009, pp. 14-24; PMID: 19010552.
    21. Balasubramanian M, Iyengar SS, Beuerman RW, Reynaud J, Wolenski P. "Real-time restoration of white-light confocal microscope optical sections", Journal of Electronic Imaging, Vol. 16, No. 3, August 2007, 033009; PMID: 20186290.


  • Untitled Document BOOK CHAPTERS
    1. Balasubramanian M, Bowd C, Zangwill LM. "Algorithms for Detecting Glaucomatous Structural Changes in the Optic Nerve Head", in Image Modeling of the Human Eye, Rajendra Acharya U, Eddi Y.K. Ng, Jasjit S. Suri, Editors, 2008, Artech House: Boston, pp.147-188.
    2. Balasubramanian M, Perkins AL, Beuerman RW, Iyengar SS. "Fractal Measures for Fungal Keratitis Diagnosis Using a White-light Confocal Microscope", in Image Modeling of the Human Eye, Rajendra Acharya U, Eddi Y.K. Ng, Jasjit S. Suri, Editors, 2008, Artech House: Boston, pp.189-202.


  • Untitled Document PEER-REVIEWED CONFERENCE ABSTRACTS
    1. Belghith A, Bowd C, Medeiros FA, Balasubramanian M, Weinreb RN, Zangwill LM, "Effects of the variability of automated segmentation algorithms on longitudinal analyses: application to the estimation of ganglion cell loss in healthy and glaucoma eyes", Association for Research in Ophthalmology and Visual Science, Annual Meeting, Denver, May 2015.
    2. Balasubramanian M, Bowd C, Weinreb RN, Kriegman DJ, Holst M, Sample PA, Zangwill LM, "Detecting Glaucomatous Progression from Localized Rates of Retinal Height Changes in Parametric and Non-Parametric Frameworks", IOVS 2012; 53; ARVO E-Abstract 238.
    3. Bowd C, Balasubramanian M, Goldbaum MH, Lee I, Medeiros FA, Zangwill LM, Girkin CA, Liebmann JM, Sample PA, Weinreb RN, "Variational Bayesian independent component analysis-mixture model (VIM) to identify patterns of glaucomatous defect in Frequency Doubling Technology (FDT) perimetry data", IOVS 2012; 53; ARVO E-Abstract 171.
    4. Goldbaum MH, Bowd C, Lee I, Balasubramanian M, Medeiros FA, Zangwill LM, Girkin CA, Liebmann JM, Sample PA, Weinreb RN, "Progression of Patterns Using Non-negative Matrix Factorization and Iso-severity Clustering of Glaucoma Patterns Improves Detection of Glaucoma Progression", IOVS 2012; 53; ARVO E-Abstract 2263.
    5. Balasubramanian M, Bowd C, Weinreb RN, Sample PA, Zangwill LM, "Localized Glaucomatous Change Detection within the Proper Orthogonal Decomposition (POD) Framework", IOVS 2011; 52; ARVO E-Abstract 170.
    6. Goldbaum MH, Lee I, Jang G, Bowd C, Balasubramanian M, Weinreb RN, Zangwill LM, Liebmann JM, Girkin CA, Sample PA, "Progression of Patterns (POP) Using Independent Component Analysis Identifies Glaucoma Progression", IOVS 2011; 52; ARVO E-Abstract 4151.
    7. Bowd C, Lee I, Medeiros FA, Balasubramanian M, Zangwill LM, Girkin CA, Liebmann JM, Weinreb RN, Sample PA, Goldbaum MH, "Predicting Glaucomatous Progression from Baseline HRT and SAP Measurements Using Relevance Vector Machine (RVM) Classifiers", IOVS 2011; 52; ARVO E-Abstract 4136.
    8. Balasubramanian M, Bowd C, Kriegman DJ, Weinreb RN, Sample PA, Zangwill LM, "Detecting Glaucomatous Changes using Only One Optic Nerve Head Scan Per Exam", IOVS 2010; 51: ARVO E-Abstract 2723.
    9. Alencar LM, Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM, Sample PA, Medeiros FA, "Comparison of the GDx GPA and the HRT TCA for Detection of Glaucomatous Progression", IOVS 2010; 51: ARVO E-Abstract 4011.
    10. Balasubramanian M, Racette L, Bowd C, Sample PA, Weinreb RN, Zangwill LM, "Relationship between Retinal Structure and Function Measurements over Time", 19th Imaging and Perimetry Society (IPS) Symposium, March 23-26, 2010, Tenerife, Spain (won the IPS-Heidelberg Young Researcher Award).
    11. Bowd C, Balasubramanian M, Weinreb RN, Zangwill LM, "Effect on HRT Topographic Change Analysis Parameter Estimates when Combining HRT-I and HRT-II Examinations in Longitudinal Series", 19th IPS Symposium, March 23-26, 2010, Tenerife, Spain.
    12. Sample PA, Jang G, Balasubramanian M, Anderson DR, Fredette MJ, Girkin CA, Liebmann JM, Bowd C, Jung TP, Zangwill LM, Weinreb RN, Goldbaum M, "Progression of Patterns (POP): Machine Learning Classifier Identifies Glaucoma Progression", 19th IPS Symposium, March 23-26, 2010, Tenerife, Spain.
    13. Tafreshi A, Racette L, Balasubramanian M, Liebmann JM, Girkin CA, Zangwill LM, Weinreb RN, Sample PA, "Comparing the Repeatability of Standard Automated Perimetry, Short-Wavelength Automated Perimetry, and Frequency-Doubling Technology Perimetry", North American Perimetric Society (NAPS), 8th meeting, New York, October 2009.
    14. Balasubramanian M, Bowd C, Sample PA, Weinreb RN, Alencar LM, Vizzeri G, Zangwill LM, "Evaluation of Heidelberg Retina Tomograph (HRT) Pixel-wise Glaucomatous Change Detection Techniques That Control for Type-1 Classification Error", IOVS 2009; 50: ARVO E-Abstract 2573.
    15. O'Leary N, Balasubramanian M, Garway-Heath DF, Crabb DP, "Developing and Testing a Heidelberg Retina Tomograph Image Simulation Method for Applications to Optimise Glaucoma Progression Algorithms", IOVS 2009; 50: ARVO E-Abstract 2249.
    16. Neal BE, Balasubramanian M, Bowd C, Vizzeri G, Sample P, Weinreb RN, Zangwill LM, "Stereometric Parameter Trend-Analysis for Detecting Progression Using Three Heidelberg Retina Tomograph Reference Planes", IOVS 2009; 50: ARVO E-Abstract 2246.
    17. Vizzeri G, Bowd C, Balasubramanian M, et al, "Determinants of Agreement between HRT TCA and Standardized Assessment of Glaucomatous Progression in the Diagnostic Innovations in Glaucoma Study", IOVS 2009; 50: ARVO E-Abstract 2248.
    18. Balasubramanian M, Bowd C, Vizzeri G, Sample PA, Weinreb RN, O'Leary N, Crabb DP, Garway-Heath DF, Zangwill LM, "Localized Glaucomatous Change Detection Using a New Permutation Test Strategy", IOVS 2008; 49: ARVO E-Abstract 3652.
    19. Bowd C, Balasubramanian M, Vizzeri G, et al, "Sensitivity and Specificity of Heidelberg Retina Tomograph (HRT) Topographic Change Analysis (TCA) Parameters", IOVS 2008; 49: ARVO E-Abstract 3759.
    20. Vizzeri G, Martinez de la Casa JM, Alencar LM, Bowd C, Balasubramanian M, Medeiros FA, Weinreb RN, Zangwill LM, "Clinicians' Agreement in Establishing Glaucomatous Progression Using the HRT Topographic Change Analysis (TCA), Trend Analysis (TA), and Moorfields Regression Analysis (MRA)", IOVS 2008; 49: ARVO E-Abstract 3653.
    21. Balasubramanian M, Bowd C, Wolenski P, Medeiros FA, Alencar LM, Sample PA. Weinreb RN, Zangwill LM, "Evaluation of a Novel Proper Orthogonal Decomposition (POD) Framework for Detecting Glaucomatous Changes in Human Subjects", IOVS 2007; 48: ARVO E-Abstract 3331.
    22. Balasubramanian M, Bowd C, Sample PA, Weinreb RN, Zangwill LM, "A Novel Multi-Scale Texture Change Detection Framework for Detecting Glaucomatous Progression of Optic Disc Topography", International Society for Imaging in the Eye, 2007.
    23. Nouri-Mahadavi K, Medeiros FA, Bowd C, Alencar LM, Vasile CG, Balasubramanian M, Sample PA, Zangwill LM, Weinreb RN, "Identifying Optic Disc Parameters That Predict Mode of Progression", IOVS 2007; 48: ARVO E-Abstract 853.
    24. Bowd C, Balasubramanian M, Medeiros FA, Alencar LM, Zangwill LM, Sample PA, Vasile C, Bourne RR, Weinreb RN, "Agreement for Detecting Change Using HRT Topographic Change Analysis (TCA), Standard Automated Perimetry (SAP) and Stereo-Photograph Assessment", IOVS 2007; 48; ARVO E-Abstract 1973.
    25. Balasubramanian M, Iyengar SS, Reynaud J, Palkama A, Beuerman RW, "Analysis of z-axis structural changes in the cow lamina cribrosa with changes in pressure using image matching", IOVS 2004; 45: ARVO E-Abstract 2178.


  • Untitled Document CONFERENCE PROCEEDINGS
    1. Belghith A, Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM, "Glaucoma Progression Detection using Variational Expectation Maximization Algorithm", Biomedical Imaging (ISBI), 2013 IEEE 10th International Symposium on, 7-11 April 2013, pp. 876-879.
    2. Khoobehi B, Ning J, Puissegur E, Bordeaux K, Balasubramanian M, Beach J. "Retinal Oxygen Saturation Evaluation by Multi-spectral Fundus Imaging", Medical Imaging 2007, Proceedings of SPIE, Vol. 6511, pp. 65110B1-6.
    3. Balasubramanian M, Perkins LA, Beuerman RW, Iyengar SS. "Fractal Dimension Based Corneal Fungal Infection Diagnosis", Applications of Digital Image Processing XXIX, Optics and Photonics 2006, Proceedings of SPIE, Vol. 6312, 631214 (1-10).
    4. Balasubramanian M, Iyengar SS, Reynaud J, Beuerman RW. "A Ringing Metric to Evaluate the Quality of Images Restored Using Iterative Deconvolution Algorithms", 18th International Conference on Systems Engineering, 2005, pp. 483-488.
    5. Balasubramanian M, Iyengar SS, Wolenski P, Reynaud J, Beuerman RW. "Adaptive Noise Filtering of White-light Confocal Microscope Images using Karhunen-Loeve Expansion", Applications of Digital Image Processing XXVIII, Optics and Photonics 2005, Proceedings of SPIE, Vol. 5909, pp.590904(1-12).
    6. Balasubramanian M, Perkins LA, Iyengar SS, Dua S, Kraft DH. "Evidence Combination for Traffic Adaptive Routing", 18th International Conference on Systems Engineering, 2005, pp.355-362.